Anti-Transferrin Receptor Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Lieferant: Bioss
BS-0988R-A680
BOSSBS-0988R-A680EA 890 EUR
BOSSBS-0988R-A680
Anti-Transferrin Receptor Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Antikörper
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.

Type: Primary
Antigen: Transferrin receptor
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 621-720/760
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse
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