Anti-ARHGAP26 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Lieferant: Bioss
BS-11248R-FITC
BOSSBS-11248R-FITCEA 900 EUR
BOSSBS-11248R-FITC
Anti-ARHGAP26 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
Antikörper
Cellular signaling by G-proteins is down-regulated by GTPase-activating proteins (GAPs), which increase the rate of GTP hydroylsis. The GTPase regulator associated with focal adhesion kinase (GRAF) has GAP activity toward Rho A and Cdc42, but not Rac1. GRAF is ubiquitously expressed with high levels in heart and brain. Expression of GRAF causes clearing of stress fibers and formation of long actin based filopodial-like extensions. Fusion of MLL with GRAF, MLL/GRAF, is included in a rare genetic subgroup of acute myeloid leukemia (AML) cases.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: ARHGAP26
Clonality: Polyclonal
Clone:
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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