Anti-AACS Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Lieferant: Bioss
BS-11383R-A647
BOSSBS-11383R-A647EA 893 EUR
BOSSBS-11383R-A647
Anti-AACS Rabbit Polyclonal Antibody (Alexa Fluor® 647)
Antikörper
ACSF1 is a 672 amino acid protein belonging to the ATP-dependent AMP-binding enzyme family. Encoded by a gene that maps to human chromosome 12q24.31, ACSF1 is highly expressed in kidney, heart and brain, and shows similar neural expression as HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase). Existing as three alternatively spliced isoforms, ACSF1 participates in ATP binding, ligase activity, acetoacetate-CoA ligase activity and nucleotide binding. The ACSF1 promoter is a known PPAR?target gene, with the nuclear receptor recruited to the ACSF1 promoter by direct interaction with stimulating protein-1 (Sp1). ACSF1 activates acetoacetate and is highly regulated by modulators that affect HMGCR and cholesterol biosynthesis.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: AACS
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 647
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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