Anti-CPT1C Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Lieferant: Bioss
BS-11416R-A488
BOSSBS-11416R-A488EA 893 EUR
BOSSBS-11416R-A488
Anti-CPT1C Rabbit Polyclonal Antibody (Alexa Fluor® 488)
Antikörper
The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into, and oxidation of fatty acids by, mitochondria. Malonyl-CoA, an intermediate in fatty acid synthesis, has been implicated as a regulatory component of the energy sensing system that feeds into hypothalmic neurons to impart energy homeostasis. Malonyl-CoA levels in the hypothalamus are dynamically regulated by fasting and feeding, altering subsequent feeding behaviour. Cpt1c, the brain-specific carnitine O-palmitoyltransferase 1, is thought to relay information about malonyl-CoA levels in hypothalamic neurons that express orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. Unlike other Cpt1 proteins, Cpt1c binds Malonyl-CoA but does not catalyse the transfer of the malonyl group from CoA to carnitine.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: CPT1C
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 488
Epitope:
Host: Rabbit
Isotype:
Reactivity:
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