Anti-Ephexin-1/EPHEXIN Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Lieferant: Bioss
BS-11458R-A680
BOSSBS-11458R-A680EA 890 EUR
BOSSBS-11458R-A680
Anti-Ephexin-1/EPHEXIN Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Antikörper
Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity).

Type: Primary
Antigen: Ephexin-1/EPHEXIN
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 451-550/710
Host: Rabbit
Isotype: IgG
Reactivity: Mouse, Rat
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