Anti-TNRC6B Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Lieferant: Bioss
BS-11489R-A647
BOSSBS-11489R-A647EA 893 EUR
BOSSBS-11489R-A647
Anti-TNRC6B Rabbit Polyclonal Antibody (Alexa Fluor® 647)
Antikörper
TNRC6B is a 1,723 amino acid protein that exists as two alternatively spliced isoforms and is thought to be involved in mRNA cleavage events. Expressed ubiquitously, TNRC6B contains one glycine/tryptophan (GW)-rich N-terminal domain, one central glutamine-rich region and one C-terminal RNA recognition motif and is encoded by a gene that maps to human chromosome 22. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: TNRC6B
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 647
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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