Anti-TNRC6B Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Lieferant: Bioss
BS-11489R-A680
BOSSBS-11489R-A680EA 890 EUR
BOSSBS-11489R-A680
Anti-TNRC6B Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Antikörper
TNRC6B is a 1723 amino acid protein that exists as two alternatively spliced isoforms and is thought to be involved in mRNA cleavage events. Expressed ubiquitously, TNRC6B contains one glycine/tryptophan (GW)-rich N-terminal domain, one central glutamine-rich region and one C-terminal RNA recognition motif and is encoded by a gene that maps to human chromosome 22. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukaemias.

Type: Primary
Antigen: TNRC6B
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 25-70/1833
Host: Rabbit
Isotype: IgG
Reactivity:
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