Anti-HS1BP3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Lieferant: Bioss
BS-11568R-A750
BOSSBS-11568R-A750EA 890 EUR
BOSSBS-11568R-A750
Anti-HS1BP3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Antikörper
HS1BP3 is a 392 amino acid protein that contains one PX (phox homology) domain, a leucine zipper, immunoreceptor tyrosine-based inhibitory motif-like motifs and multiple proline-rich regions. Expressed primarily in brain, HS1BP3 is encoded by a gene mapping to human chromosome 2p24.1. The gene encoding HS1BP3 is frequently mutated in familial essential tremor, a disorder characterised by kinetic tremor the the hands, voice or head, though there is no correlation to Parkinson disease. HS1BP3 interacts with HAX-1 SH3 domain, and may also play a role in the regulation of catecholamine and serotonin metabolism. Acting as a regulator of IL-2 Signalling, HS1BP3 is likely involved in lymphocyte activation.

Type: Primary
Antigen: HS1BP3
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 51-130/392
Host: Rabbit
Isotype: IgG
Reactivity: Human
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