Anti-AAAS Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Lieferant: Bioss
BS-11807R-A350
BOSSBS-11807R-A350EA 893 EUR
BOSSBS-11807R-A350
Anti-AAAS Rabbit Polyclonal Antibody (Alexa Fluor® 350)
Antikörper
Aladin (Adracalin) belongs to a family of WD repeat-containing proteins. These proteins have a wide variety of functions, including signal transduction regulation, RNA processing and transcription. Aladin plays a role in peripheral and central nervous system development. It is widely expressed, with the highest expression seen in pituitary gland, corpus callosum, cerebellum, adrenal gland and gastrointestinal structures. Defects in Aladin cause the autosomal recessive disorder achalasia-addisonianism-alacrima (triple A) syndrome. Triple A syndrome is characterized by achalasia, alacrima and adrenocortico-tropin-resistant adrenal insufficiency. Robust expression in neural systems associated with cognitive, motor and sensory functions is consistent with the myriad of symptoms experienced by patients with triple A syndrome.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: AAAS
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 350
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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