Anti-GRIK3 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Lieferant: Bioss
BS-12007R-A350
BOSSBS-12007R-A350EA 893 EUR
BOSSBS-12007R-A350
Anti-GRIK3 Rabbit Polyclonal Antibody (Alexa Fluor® 350)
Antikörper
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem, whereas the four epsilon subunits display limited distribution.

Recommended Dilutions: Flow Cytometry: 1:20-100; IF(IHC-P): 1:50-200

Type: Primary
Antigen: GRIK3/GLR7
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 350
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
Bestellen

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Mehr About VWR