Anti-KCNT2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Lieferant: Bioss
BS-12177R-A647
BOSSBS-12177R-A647EA 893 EUR
BOSSBS-12177R-A647
Anti-KCNT2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)
Antikörper
Voltage-gated K+ channels in the plasma membrane are important regulators of electrical signaling, controlling the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. KCNT2 is a 1,135 amino acid multi-pass transmembrane protein belonging to the potassium channel family (calcium-activated subfamily) of proteins. KCNT2 produces rapidly activating outward rectifier potassium currents in reponse to high intracellular sodium and chloride levels. Its channel activity is inhibited by ATP, inhalation anesthetics, such as isoflourane, and upon stimulation of G-protein coupled receptors, such as mAChR M1 and GluR-1. There are four isoforms of KCNT2 that are produced as a result of alternative splicing events.

Recommended Dilutions: Flow Cytometry: 1:20-100; IF(IHC-P): 1:50-200

Type: Primary
Antigen: KCNT2
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 647
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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