Anti-SNX5 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Lieferant: Bioss
BS-12248R-A680
BOSSBS-12248R-A680EA 890 EUR
BOSSBS-12248R-A680
Anti-SNX5 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Antikörper
Sorting nexin 1 (SNX1) is a member of a large family of hydrophilic proteins that interact with a variety of receptor types and are involved in intracellular trafficking. SNX1 and the related splice variant, SNX1A, bind the epidermal growth factor (EGF) receptor, facilitate its transport to lysosome, and thereby contribute to the degradation of the receptor. SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain. These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases. These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes. The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors.

Type: Primary
Antigen: SNX5
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 2-75/404
Host: Rabbit
Isotype: IgG
Reactivity:
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