Anti-HtrA2/Omi Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Lieferant: Bioss
BS-1271R-A750
BOSSBS-1271R-A750EA 890 EUR
BOSSBS-1271R-A750
Anti-HtrA2/Omi Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Antikörper
Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins(also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Isoform 2 seems to be proteolytically inactive. [CATALYTIC ACTIVITY] Cleavage of non-polar aliphatic amino-acids at the P1 position, with a preference for Val, Ile and Met. At the P2 and P3 positions, Arg is selected most strongly with a secondary preference for other hydrophilic residues. [SUBUNIT] Homotrimer. Interacts with MXI2. The mature protein, but not the precursor, binds to BIRC2, BIRC3 and XIAP.

Type: Primary
Antigen: HtrA2/Omi
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 355-458/458
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
Bestellen

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Mehr About VWR