Anti-Beta cellulin Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Lieferant: Bioss
BS-12864R-A680
BOSSBS-12864R-A680EA 890 EUR
BOSSBS-12864R-A680
Anti-Beta cellulin Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Antikörper
Betacellulin (BTC), a member of the epidermal growth factor (EGF) family, was originally identified as a growth-promoting factor in the conditioned medium of a mouse pancreatic-cell carcinoma (insulinoma) cell line and has since been identified in humans. BTC is synthesised as a large transmembrane precursor molecule that can be cleaved proteolytically to release the soluble form of BTC or function as membrane-anchored growth factors in juxtacrine Signalling. BTC, in addition to stimulating homodimers of ErbB-1 and ErbB-4, is capable of binding and activating all possible combinations of heterodimeric ErbB receptors including the oncogenic ErbB-2/ErbB-3 complex. BTC is also expressed in some human malignancies and may have an important role in tumour growth progression.

Type: Primary
Antigen: Beta cellulin
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 1-100/178
Host: Rabbit
Isotype: IgG
Reactivity: Mouse
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