Anti-BMP8B Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Lieferant: Bioss
BS-12873R-A488
BOSSBS-12873R-A488EA 893 EUR
BOSSBS-12873R-A488
Anti-BMP8B Rabbit Polyclonal Antibody (Alexa Fluor® 488)
Antikörper
Bone morphogenic proteins (BMPs) are members of the TGF Beta superfamily. BMPs are involved in the induction of cartilage and bone formation. In vivo studies have shown that BMP-2 (also designated BMP-2A) and BMP-3 can independently induce cartilage formation. Smad3 association with the TGF Beta receptor complex and Smad1 translocation to the nucleus are observed after the addition of BMP-4 (also designated BMP-2B), suggesting that BMP-4 may play a role in activation of the Smad pathway. BMP-5, BMP-6 and BMP-7 all share high sequence homology with BMP-2, indicating that they each may be able to induce cartilage formation. BMP-8 (also designated OP-2) is thought to be involved in early development, as detectable expression has not been found in adult organs.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: BMP8B
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 488
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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