Anti-CYP2A6 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Lieferant: Bioss
BS-12923R-A647
BOSSBS-12923R-A647EA 893 EUR
BOSSBS-12923R-A647
Anti-CYP2A6 Rabbit Polyclonal Antibody (Alexa Fluor® 647)
Antikörper
P450 enzymes constitute a family of monooxygenase enzymes that are involved in the metabolism of a wide array of endogenous and xenobiotic compounds (1). Several P450 enzymes have been classified by sequence similarities as members of the CYP1A and CYP2A subfamilies (2). NADPH cytochrome P450 reductase is a microsomal enzyme responsible for the transfer of electrons from NADPH to cytochrome P450 enzymes during the P450 catalytic cycle (3,4). NADPH cytochrome P450 reductase is localized to the endoplasmic reticulum where it is also able to transfer electrons to heme oxygenase and cytochrome b5 (5,6). NADPH cytochrome P450 reductase is structurally related to two separate flavoprotein families, ferredoxin nucleotide reductase (FNR) and flavodoxin (7). Electron transfer of NADPH cytochrome P450 reductase requires the binding of two flavin cofactors, FAD and FMN, to the FNR and flavodoxin domains, respectively (8).

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: CYP2A6
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 647
Epitope:
Host: Rabbit
Isotype:
Reactivity:
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