Anti-FMO3 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Lieferant: Bioss
BS-13186R-A647
BOSSBS-13186R-A647EA 893 EUR
BOSSBS-13186R-A647
Anti-FMO3 Rabbit Polyclonal Antibody (Alexa Fluor® 647)
Antikörper
The Flavin containing monooxygenase family consists of five gene products, FMO1-5, that are major enzymatic oxidants involved in the metabolism of various therapeutics. Located in the liver, FMO3 is a hepatic microsomal enzyme that oxygenates soft nucleophiles such as secondary and tertiary amines. Through its N-oxygenase capabilities, FMO3 acts on a variety of xenobiotics to catalyze oxidative digestion. Defects in the FMO3 gene are the primary cause of trimethylaminuria (TMAuria), an inborn error of metabolism associated with a fishy body odor emitting from sweat, urine and breath. Genetic mutations in FMO3 lead to the N-oxidation of amino-trimethylamine derived from food products, thus producing the malodor associated with TMAuria.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: FMO3
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 647
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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