Anti-Glutamyl Prolyl tRNA synthetase/ProRS Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Lieferant: Bioss
BS-13393R-A750
BOSSBS-13393R-A750EA 890 EUR
BOSSBS-13393R-A750
Anti-Glutamyl Prolyl tRNA synthetase/ProRS Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Antikörper
Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the multisynthetase complex and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.

Type: Primary
Antigen: Glutamyl Prolyl tRNA synthetase/ProRS
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 651-750/1512
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse; Rat
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