Anti-PTGDR2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Lieferant: Bioss
BS-13537R-A647
BOSSBS-13537R-A647EA 893 EUR
BOSSBS-13537R-A647
Anti-PTGDR2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)
Antikörper
Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, ADRBK1/GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: PTGDR2
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 647
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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