Anti-Ku-80 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Lieferant: Bioss
BS-1358R-A680
BOSSBS-1358R-A680EA 890 EUR
BOSSBS-1358R-A680
Anti-Ku-80 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Antikörper
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Type: Primary
Antigen: Ku-80
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 301-450/732
Host: Rabbit
Isotype: IgG
Reactivity: Others
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