Anti-Arfaptin 2 Rabbit Polyclonal Antibody (Cy7®)

Lieferant: Bioss
BS-1442R-CY7
BOSSBS-1442R-CY7EA 893 EUR
BOSSBS-1442R-CY7
Anti-Arfaptin 2 Rabbit Polyclonal Antibody (Cy7®)
Antikörper
ARFIP2 is a ubiquitously expressed protein implicated in mediating cross talk between RAC and ARF small GTPases. It has been shown that ARFIP2 binds specifically to GTP-bound ARF1 and ARF6, but binds to Rac-GTP and Rac-GDP with similar affinities. The X-ray structure of arfaptin reveals an elongated, crescent-shaped dimer of 3-helix coiled-coils. Structures of arfaptin with Rac bound to either GDP or the slowly hydrolysable analog GMPPNP show that the switch regions adopt similar conformations in both complexes.

Type: Primary
Antigen: Arfaptin 2
Clonality: Polyclonal
Clone:
Conjugation: Cy7
Public Immunogen Range: 221-341/341
Host: Rabbit
Isotype: IgG
Reactivity:
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