Anti-Hamartin Rabbit Polyclonal Antibody (HRP)

Lieferant: Bioss
BS-15406R-HRP
BOSSBS-15406R-HRPEA 900 EUR
BOSSBS-15406R-HRP
Anti-Hamartin Rabbit Polyclonal Antibody (HRP)
Antikörper
Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder characterised by mental retardation and the widespread development of distinctive tumors termed hamartomas. Two different genetic loci have been linked to TSC; one of these loci, the tuberous sclerosis-2 gene (TSC2), encodes a protein called tuberin and the other loci, tuberous sclerosis-1 gene (TSC1), encodes a protein called hamartin. Tuberin and hamartin interact with each other forming a cystoplasmic complex. Hamartin interacts with the ezrin-radixin-moesin (ERM) family of actin-binding proteins and inhibition of hamartin activity results in loss of cell adhesion. Hamartin is present in most adult tissues with strong expression in brain, heart, and kidney.

Type: Primary
Antigen: Hamartin
Clonality: Polyclonal
Clone:
Conjugation: HRP
Public Immunogen Range: 701-800/1164
Host: Rabbit
Isotype: IgG
Reactivity:
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