Anti-HGD Rabbit Polyclonal Antibody (ALEXA FLUOR® 555)

Lieferant: Bioss
BS-15472R-A555
BOSSBS-15472R-A555EA 893 EUR
BOSSBS-15472R-A555
Anti-HGD Rabbit Polyclonal Antibody (ALEXA FLUOR® 555)
Antikörper
HGD is a 445 amino acid protein that belongs to the homogentisate dioxygenase family and is involved in the pathway of amino acid degradation. Expressed at high levels in kidney, colon, liver, prostate and small intestine, HGD uses iron as a cofactor to catalyse the oxygen-dependent conversion of homogentisate to 4-maleylacetoacetate, a reaction that is the fourth step in the creation of L-phenylalanine from fumarate and acetoacetic acid. Defects in the gene encoding HGD are the cause of alkaptonuria (AKU), an autosomal recessive disorder that is characterised by urine that turns dark on standing and alkalinisation, black ochronotic pigmentation of cartilage and collagenous tissues and spine arthritis.

Type: Primary
Antigen: HGD
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 555
Public Immunogen Range: 351-445/445
Host: Rabbit
Isotype: IgG
Reactivity: Mouse
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