Anti-DNA Ligase IV/LIG4 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Lieferant: Bioss
BS-1677R-A750
BOSSBS-1677R-A750EA 890 EUR
BOSSBS-1677R-A750
Anti-DNA Ligase IV/LIG4 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Antikörper
Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

Type: Primary
Antigen: DNA Ligase IV/LIG4
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 51-150/911
Host: Rabbit
Isotype: IgG
Reactivity: Human
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