Anti-SPHK1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Lieferant: Bioss
BS-2652R-A350
BOSSBS-2652R-A350EA 901 EUR
BOSSBS-2652R-A350
Anti-SPHK1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)
Antikörper
Sphingosine-1-phosphate (SPP) is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.[supplied by OMIM].

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: SPHK1
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 350
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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