Anti-FANCD2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Lieferant: Bioss
BS-2738R-A350
BOSSBS-2738R-A350EA 893 EUR
BOSSBS-2738R-A350
Anti-FANCD2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)
Antikörper
Fanconi Anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomycin C (MMC). The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation.DNA damage activates the monoubiquitination of FANC D2, targeting nuclear foci containing the BRCA 1 protein.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: FANCD2
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 350
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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