Anti-GGT1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Lieferant: Bioss
BS-2976R-A680
BOSSBS-2976R-A680EA 890 EUR
BOSSBS-2976R-A680
Anti-GGT1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Antikörper
Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds. The metabolism of glutathione releases free glutamate and the dipeptide, cysteinyl-glycine, which is hydrolysed to cysteine and glycine by dipeptidases. In the presence of high concentrations of dipeptides and some amino acids, can also catalyse a transpeptidation reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defence mechanism. Isoform 3 seems to be inactive.

Type: Primary
Antigen: GGT1
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 351-460/569
Host: Rabbit
Isotype: IgG
Reactivity: Human
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