Anti-Pin1 Ser16 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Lieferant: Bioss
BS-3354R-A750
BOSSBS-3354R-A750EA 1350 EUR
BOSSBS-3354R-A750
Anti-Pin1 Ser16 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Antikörper
Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. catalyses pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation. Binds and targets PML and BCL6 for degradation in a phosphorylation-dependent manner.

Type: Primary
Antigen: Pin1 Ser16
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range:
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse; Rat
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