Anti-PEA15 Rabbit Polyclonal Antibody

Lieferant: Bioss
BS-3524R
BOSSBS-3524REA 725 EUR
BOSSBS-3524R
Anti-PEA15 Rabbit Polyclonal Antibody
Antikörper
PED/PEA 15 (Phosphoprotein Enriched in Diabetes/Phosphoprotein Enriched in Astrocytes 15 kDa) is a widely expressed 15 kDa protein comprised of an N terminal region containing a canonical Death Effector Domain (DED) sequence and a nuclear export signal, and a C terminal region containing two serine phosphorylation sites. PED/PEA 15 has been implicated in the regulation of multiple cellular processes including apoptosis, integrin activation, and insulin sensitive glucose transport in insulin responsive cells. Phosphorylation of both serine 104 (a Protein Kinase C site) and serine 116 (a substrate of CaMKII and Akt) is required for PED/PEA 15 function.

IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Type: Primary
Antigen: PEA15
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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