Anti-CYP2R1 Rabbit Polyclonal Antibody (Cy7®)

Lieferant: Bioss
BS-3900R-CY7
BOSSBS-3900R-CY7EA 900 EUR
BOSSBS-3900R-CY7
Anti-CYP2R1 Rabbit Polyclonal Antibody (Cy7®)
Antikörper
CYP2R1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are mono-oxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor.Defects in CYP2R1 are a cause of 25-hydroxyvitamin D(3) deficiency, also known as pseudovitamin D(3) deficiency rickets due to 25-hydroxylase deficiency. First described in patients who had rickets at a young age despite a history of adequate vitamin D intake. The patients sera had low calcium concentrations, low phosphate concentrations, elevated alkaline phosphatase activity and low levels of 25-hydroxyvitamin D.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: CYP2R1
Clonality: Polyclonal
Clone:
Conjugation: Cy7®
Epitope:
Host: Rabbit
Isotype:
Reactivity:
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