Anti-Filamin A Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Lieferant: Bioss
BS-4105R-A750
BOSSBS-4105R-A750EA 890 EUR
BOSSBS-4105R-A750
Anti-Filamin A Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Antikörper
Caldesmon, Filamin 1, Nebulin and Villin are differentially expressed and regulated Actin binding proteins. Both muscular (CDh) and non-muscular (CDl) forms of Caldesmon have been identified and each has been shown to bind to Actin as well as to calmodulin and Myosin. CDh is expressed predominantly on thin filaments in smooth muscle, whereas CDl is widely expressed in non-muscle tissues and cells. Filamin 1, which is ubiquitously expressed and exists as a homodimer, functions to crosslink Actin to filaments. Nebulin is a large filamentous protein specific to muscle tissue that may function as a ruler for filament length. Several isoforms of Nebulin are produced by alternative exon usage. Villin is Ca2+-regulated and is the major structural component of the brush border of absorptive cells.

Type: Primary
Antigen: Filamin A
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 1851-1960/2647
Host: Rabbit
Isotype: IgG
Reactivity: Human
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