Anti-CHEK1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Lieferant: Bioss
BS-5251R-A488
BOSSBS-5251R-A488EA 921 EUR
BOSSBS-5251R-A488
Anti-CHEK1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)
Antikörper
Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. May also negatively regulate cell cycle progression during unperturbed cell cycles. This regulation is achieved by a number of mechanisms that together help to preserve the integrity of the genome. Recognizes the substrate consensus sequence [R-X-X-S/T]. Binds to and phosphorylates CDC25A, CDC25B and CDC25C. Phosphorylation of CDC25A at 'Ser-178' and 'Thr-507' and phosphorylation of CDC25C at 'Ser-216' createsMore Product Information
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