Anti-CDK2 Rabbit Polyclonal Antibody (Cy3®)

Lieferant: Bioss
BS-5277R-CY3
BOSSBS-5277R-CY3EA 902 EUR
BOSSBS-5277R-CY3
Anti-CDK2 Rabbit Polyclonal Antibody (Cy3®)
Antikörper
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. cdk2 is a cell cycle protein closely related to Cdc2 (cdk1) that has proved useful as a marker of proliferation. cdk2 binds cyclin type A and E proteins and controls progression into S-phase.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: CDK2
Clonality: Polyclonal
Clone: 0
Conjugation: Cy3®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity:
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