Anti-GRIA2 Rabbit Polyclonal Antibody

Lieferant: Bioss
BS-5359R
BOSSBS-5359REA 743 EUR
BOSSBS-5359R
Anti-GRIA2 Rabbit Polyclonal Antibody
Antikörper
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate(AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing(CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene.

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Type: Primary
Antigen: Gria2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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