Anti-GRIA2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Lieferant: Bioss
BS-5359R-A555
BOSSBS-5359R-A555EA 922 EUR
BOSSBS-5359R-A555
Anti-GRIA2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)
Antikörper
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate(AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing(CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: Gria2
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 555
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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