Anti-HOXA5 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Lieferant: Bioss
BS-5713R-A488
BOSSBS-5713R-A488EA 893 EUR
BOSSBS-5713R-A488
Anti-HOXA5 Rabbit Polyclonal Antibody (Alexa Fluor® 488)
Antikörper
HOXA5 upregulates both p53 promoter-reporter constructs and endogenous p53 synthesis, leading to apoptosis. HOXA5 is detectable in approximately one-third of primary tumors. Lack of HOXA5 expression strongly correlates with methylation of its promoter region, suggesting a causal role for methylation in the silencing of HOXA5 gene expression. HOXA5 expression is an important step in tumorigenesis and loss of expression of p53 in human breast cancer may be primarily due to lack of expression of HOXA5.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: HOXA5
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 488
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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