Anti-PCDHGB5 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Lieferant: Bioss
BS-5827R-A680
BOSSBS-5827R-A680EA 890 EUR
BOSSBS-5827R-A680
Anti-PCDHGB5 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Antikörper
PCDHGB5 is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organisation, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Type: Primary
Antigen: PCDHGB5
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 21-120/923
Host: Rabbit
Isotype: IgG
Reactivity:
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