Anti-HRAS+KRAS Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Lieferant: Bioss
BS-6165R-A750
BOSSBS-6165R-A750EA 893 EUR
BOSSBS-6165R-A750
Anti-HRAS+KRAS Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Antikörper
The KRAS gene encodes the human cellular homolog of a transforming gene isolated from the Kirsten rat sarcoma virus. The RAS proteins are GDP/GTP-binding proteins that act as intracellular signal transducers. The most well-studied members of the RAS (derived from 'RAt Sarcoma' virus) gene family include KRAS, HRAS, and NRAS. These genes encode immunologically related proteins with a molecular mass of 21 kD and are homologs of rodent sarcoma virus genes that have transforming abilities. While these wildtype cellular proteins in humans play a vital role in normal tissue signaling, including proliferation, differentiation, and senescence, mutated genes are potent oncogenes that play a role in many human cancers.

Type: Primary
Antigen: HRAS+KRAS
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 51-150/189
Host: Rabbit
Isotype: IgG
Reactivity: Human
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