Anti-HRAS Rabbit Polyclonal Antibody (Cy5®)

Lieferant: Bioss
BS-6165R-CY5
BOSSBS-6165R-CY5EA 900 EUR
BOSSBS-6165R-CY5
Anti-HRAS Rabbit Polyclonal Antibody (Cy5®)
Antikörper
The KRAS gene encodes the human cellular homolog of a transforming gene isolated from the Kirsten rat sarcoma virus. The RAS proteins are GDP/GTP-binding proteins that act as intracellular signal transducers. The most well-studied members of the RAS (derived from 'RAt Sarcoma' virus) gene family include KRAS, HRAS, and NRAS. These genes encode immunologically related proteins with a molecular mass of 21 kD and are homologs of rodent sarcoma virus genes that have transforming abilities. While these wildtype cellular proteins in humans play a vital role in normal tissue signaling, including proliferation, differentiation, and senescence, mutated genes are potent oncogenes that play a role in many human cancers.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: HRAS
Clonality: Polyclonal
Clone:
Conjugation: Cy5®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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