Anti-CCT8L2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Lieferant: Bioss
BS-6406R-A350
BOSSBS-6406R-A350EA 893 EUR
BOSSBS-6406R-A350
Anti-CCT8L2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)
Antikörper
CESK1, also known as CCT8L2 (chaperonin containing TCP1, subunit 8 theta-like 2), is a 557 amino acid protein that localizes to the cytoplasm and is thought to function as a molecular chaperone, possibly assisting protein folding after ATP hydrolysis. CESK1 belongs to the TCP-1 chaperonin family and is encoded by a gene which maps to human chromosome 22. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein Bcr-Abl, a potent cell proliferation activator found in several types of leukemias.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: CCT8L2
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 350
Epitope:
Host: Rabbit
Isotype: IgG1
Reactivity: Human
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