Anti-CATSPER4 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Lieferant: Bioss
BS-6422R-A750
BOSSBS-6422R-A750EA 893 EUR
BOSSBS-6422R-A750
Anti-CATSPER4 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Antikörper
CatSpers (cation channel, sperm associated proteins) are ion transport proteins located on the surface of sperm cells in the principal piece of the sperm tail. CatSpers are vital to sperm motility, fertilisation and cAMP-mediated calcium influx in sperm. There are four CatSper proteins in mammalian sperm, namely CatSper (or CatSper1), CatSper2, CatSper3 and CatSper4. CatSper proteins contain a single, six-transmembrane-spanning segment and exhibit the voltage-dependent Ca2+ channel four-repeat structure. CatSper proteins are believed to assemble into a heterotetrameric complex, forming an alkalinisation-activated Ca2+-selective channel. Mutations in any of the genes encoding CatSper family proteins can result in male infertility. CatSper3 plays an important role in the hyperactivated motility of sperm cells, a process that is required in the preparation of sperm for fertilisation.

Type: Primary
Antigen: CATSPER4
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 101-200/472
Host: Rabbit
Isotype: IgG
Reactivity:
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