Anti-MRGPRX1/3/4 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Lieferant: Bioss
BS-6606R-A750
BOSSBS-6606R-A750EA 893 EUR
BOSSBS-6606R-A750
Anti-MRGPRX1/3/4 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Antikörper
There are four members (MRGX1-4) in the human MRGX familly. MRGX1 and MRGX2 receptors stimulate both G Alpha q- and G Alpha i -regulated pathways, while MRGX3 and MRGX4 receptors mainly activate G Alpha q-regulated pathways. G Alpha q proteins are involved in the calcium-signaling pathway downstream of the MRGX receptors. MRGX receptors are unique in that they are expressed in a subset of small dorsal root and trigeminal sensory neurons. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway.

Type: Primary
Antigen: MRGPRX1/3/4
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 21-120/322
Host: Rabbit
Isotype: IgG
Reactivity: Human
Bestellen

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Mehr About VWR