Anti-FGFR1OP Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Lieferant: Bioss
BS-8345R-A750
BOSSBS-8345R-A750EA 893 EUR
BOSSBS-8345R-A750
Anti-FGFR1OP Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Antikörper
FOP, is a 399 amino acid protein that localises to the centrosome and contains one LisH domain. Expressed ubiquitously with highest expression in kidney, heart, muscle, colon, liver, testis and pancreas, FOP functions as a homodimer that interacts with EB1 and CEP350 and is essential for anchoring microtubules to centrosomes. Chromosomal aberrations that involve the FOP gene are associated with the pathogenesis of stem cell myeloproliferative disorder (MPD), a condition that is characterised by eosinophilia and myeloid hyperplasia and ultimately leads to acute myeloid leukemia. FOP is expressed as multiple isoforms that are produced by alternative splicing events.

Type: Primary
Antigen: FGFR1OP
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 151-250/399
Host: Rabbit
Isotype: IgG
Reactivity:
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