Anti-Viperin Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Lieferant: Bioss
BS-8718R-A750
BOSSBS-8718R-A750EA 893 EUR
BOSSBS-8718R-A750
Anti-Viperin Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Antikörper
RSAD2 is a 361 amino acid protein that is involved in antiviral defense against pathogens such as Hep C, Cytomegalovirus and HIV-1. Localised to the cytosolic side of the endoplasmic reticulum and relocated to the Golgi apparatus upon viral infection, RSAD2 is thought to prevent viral budding by disrupting lipid rafts at the plasma membrane and supporting the Interferon-induced antiviral state of the cell. Additionally, RSAD2 can bind to and inactivate FDPS (an enzyme that is crucial for the synthesis of cholesterol and geranylated and farnesylated proteins), thereby playing a role in lipid synthesis. Overexpression of RSAD2 leads to abnormal lipid accumulation that is associated with atherosclerosis, a chronic inflammatory disease characterised by hardened arteries.

Type: Primary
Antigen: Viperin
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 265-361/361
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse; Rat
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