Anti-SARM1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Lieferant: Bioss
BS-9001R-A680
BOSSBS-9001R-A680EA 893 EUR
BOSSBS-9001R-A680
Anti-SARM1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Antikörper
Negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway which plays a pivotal role in activating axonal degeneration following injury. Promotes Wallerian degeneration an injury-induced axonal death pathway which involves degeneration of an axon distal to the injury site. Can activate neuronal death in response to stress. Regulates dendritic arborisation through the MAPK4-JNK pathway. Involved in innate immune response. Inhibits both TICAM1/TRIF- and MYD88-dependent activation of JUN/AP-1, TRIF-dependent activation of NF-kappa-B and IRF3, and the phosphorylation of MAPK14/p38.

Type: Primary
Antigen: SARM1
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 321-420/724
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse; Rat
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