Anti-PDXK Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Lieferant: Bioss
BS-9035R-A647
BOSSBS-9035R-A647EA 893 EUR
BOSSBS-9035R-A647
Anti-PDXK Rabbit Polyclonal Antibody (Alexa Fluor® 647)
Antikörper
Pyridoxal kinase belongs to the pyridoxine kinase family and phosphorylates vitamin B6, a step necessary for the conversion of vitamin B6 to pyridoxal 5’ phosphate (PLP), the active form of vitamin B6. PLP acts as a coenzyme and functions to maintain homeostasis. Pyridoxal kinase is a 312-amino acid cytoplasmic protein that may act as a homodimer and is expressed ubiquitously. There are three known isoforms of pyridoxal kinase, and isoform 3 expression is observed in adult testis and spermatozoa. The optimum pH for pyridoxal kinase is between 5.5 and 6.0. PDXK, the gene that encodes the pyridoxal kinase protein, maps to chromosome 21q22.3 and may be a candidate gene for autoimmune polyglandular disease type 1, a genetic disorder that has been mapped to the same region on chromosome 21.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: PDXK
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 647
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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