Anti-TRPM8 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Lieferant: Bioss
BS-9045R-A680
BOSSBS-9045R-A680EA 1350 EUR
BOSSBS-9045R-A680
Anti-TRPM8 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Antikörper
Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage-dependent gating. Activated upon depolarisation, changes in temperature resulting in graded shifts of its voltage-dependent activation curves. The chemical agonists menthol functions as a gating modifier, shifting activation curves towards physiological membrane potentials. Temperature sensitivity arises from a tenfold difference in the activation energies associated with voltage-dependent opening and closing.

Type: Primary
Antigen: TRPM8
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 81-180/1104
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse; Rat
Bestellen

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Mehr About VWR