Anti-BMP10 Rabbit Polyclonal Antibody (Cy7®)

Lieferant: Bioss
BS-9447R-CY7
BOSSBS-9447R-CY7EA 897 EUR
BOSSBS-9447R-CY7
Anti-BMP10 Rabbit Polyclonal Antibody (Cy7®)
Antikörper
Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: BMP10
Clonality: Polyclonal
Clone:
Conjugation: Cy7®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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