Anti-FNTA Rabbit Polyclonal Antibody (Cy5®)

Lieferant: Bioss
BS-9547R-CY5
BOSSBS-9547R-CY5EA 900 EUR
BOSSBS-9547R-CY5
Anti-FNTA Rabbit Polyclonal Antibody (Cy5®)
Antikörper
FNTA, also known as CAAX farnesyltransferase (FTase), attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins that end in the so-called CAAX box, where C is cysteine, A is usually but not always an aliphatic amino acid, and X is typically methionine or serine. This type of posttranslational modification provides a mechanism for membrane localization of proteins that lack a transmembrane domain. This enzyme has the remarkable property of farnesylating peptides as short as four residues in length that conform to the CAAX consensus sequence. FNTA is also a specific cytoplasmic interactor of the transforming growth factor-beta and activin type I receptors. It is likely to be a key component of the signaling pathway which involves p21ras, an important substrate for farnesyltransferase.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: PGGT1A
Clonality: Polyclonal
Clone:
Conjugation: Cy5®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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