Anti-CAMK2D Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Lieferant: Bioss
BS-9921R-A680
BOSSBS-9921R-A680EA 893 EUR
BOSSBS-9921R-A680
Anti-CAMK2D Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Antikörper
The Ca²⁺/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is a ubiquitously expressed serine/threonine protein kinase that is activated by Ca²⁺and calmodulin (CaM) and has been implicated in regulation of the cell cycle and transcription. There are four CaMKII isozymes designated å, , © and ∂, which may or may not be co-expressed in the same tissue type. CaMKIV is stimulated by Ca²⁺ and CaM but phosphorylation by a CaMK is also required for full activation. Stimulation of the T cell receptor CD3 Signalling complex with an anti-CD3 monoclonal antibody leads to a 10 to 40 fold increase in CaMKIV activity. An additional kinase, CaMKK, functions to activate CaMKI through the specific phosphorylation of the regulatory threonine residue at position 177.

Type: Primary
Antigen: CAMK2D
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 271-370/499
Host: Rabbit
Isotype: IgG
Reactivity: Mouse, Rat
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